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副教授/副研究员
当前位置： 首页 > 科学研究 > 科技队伍 > 副教授/副研究员

姓 名：徐华栋
职 务：
电 话：021-62232487
邮 件：huadongxu@gmail.com
研究团队主页：
个人主页: http://faculty.ecnu.edu.cn/xuhuadong/Info_cn.html
个人简介

副研究员，硕士生导师，2007.11于伊利诺伊大学芝加哥分校获有机化学博士学位。2007.11-2009.2 在威斯康星大学药学院从事博士后研究， 2009.6-2010.1 上海泓博智源医药技术有限公司任高级研究员，2010.2-至今在华东师范大学小分子药物研究所工作。长期从事有机化学基础研究，在不对称催化合成、糖化学以及天然产物的合成等领域开展了大量卓有成效的工作并取得了一系列高水平创新性成果。

代表论著

1.     DABCO-Catalyzed 1‚4-Bromolactonization of Conjugated Enynes: Highly Stereoselective Formation of a Stereogenic Center and an Axially Chiral Allene. Zhang‚ W.‚ Xu‚ H.‚ Xu‚ H. and Tang‚ W. J. Am. Chem. Soc. 2009‚ 131‚ 3832-3833.

2.     Thermodynamic Control of the Electrocyclic Ring Opening of Cyclobutenes: C=X Substituents at C-3 Mask the Kinetic Torquoselectivity.Um‚ J. M.‚ Xu‚ H.‚ Houk‚ K. N. and Tang‚ W. J. Am. Chem. Soc. 2009‚ 131‚ 6664-6665.

3.     Highly Selective Synthesis of Cyclobutenes via Transition Metal Catalyzed Rearrangement of Cyclopropyl Metal Carbenes. Xu‚ H.‚ Zhang‚ W.‚ Shu‚ D.‚ Werness‚ J. B. and Tang‚ W. Angew. Chem. 2008‚ 47‚ 8933-8936.

4.     Total synthesis and structural verification of some novel branched alkanes with quaternary carbons isolated from diverse geological sources.Crich‚ D.‚ Xu‚ H. and Kenig‚ F. J. Org. Chem. 2006‚ 71‚ 5016-5019.

5.     Direct stereocontrolled synthesis of 3-amino-3-deoxy-β-mannopyranosides: importance of the nitrogen protecting group on stereoselectivity. Crich‚ D.‚ Xu‚ H. J. Org. Chem. 2007 72‚ 5183-5192.

6.     Chiral 1‚2‚3‚4-tetrahydroquinolinyl-oxazoline ligands for Ru-catalyzed asymmetric transfer hydrogenation of ketones. Zhou‚ Y.‚ Tang‚ F.‚ Xu‚ H.‚ Wu‚ X.‚ Ma‚ J. and Zhou Q. Tetrahedron: Asymmetry; 2002‚ 13‚ 469-473.

7.     Remote substituent effect in palladium/pyridinyl-oxazolines catalyzed asymmetric allylic alkylation. Li‚ Z.‚ Tang‚ F.‚ Xu‚ H.‚ Wu‚ X.‚ Zhou‚ Q.‚ Chan‚ A. S. C. J. Mol. Catal. A. 2002‚ 1-7‚ 3756.

8.     A short synthesis of the HIV-protease inhibitor nelfinavir via a distereoselective addition of ammonia to the α-β-unsaturated sulfoxide derived from (R)-glyceraldehyde acetonide. Ma‚ D.‚ Zou‚ B.‚ Zhu‚ W. and Xu‚ H. Tetrahedron Lett.; 2002‚ 43‚ 8511-8513.

9.     Asymmetric hydroarylation of norbornene derivatives catalyzed by palladium complexes of chiral quinolinyl-oxazolines. Wu‚ X.‚ Xu‚ H.‚ Tang‚ F. and Zhou‚ Q. Tetrahedron Asymmetry; 2001‚ 12‚ 2565-2569.

10. Enantioselecive Heck-type hydroarylation of norbornene with phenyl iodide catalyzed by palladium/quinolinyloxazolines. Wu‚ X.‚ Xu‚ H.‚ Zhou‚ Q. and Chan‚ A. S. C. Tetrahedron: Asymmetry; 2000‚ 11‚ 1255-1257.