刘顺英

学术简介

主要从事不对称多组分反应、超分子识别和催化研究及其在药物发现中的应用研究。在相关研究领域发表SCI研究论文41篇，累计他人引用400余次， 2007年获第一届“中国百篇最具影响优秀国际学术论文”奖（第1作者）、2008年获Tetrahedron Asymm.学术杂志2005-2008年度最高论文引用奖（第1作者）、2009年获教育部自然科学二等奖（第3完成人）。参与完成国家自然基金重点项目1项、973课题1项、上海市重点项目2项，主持国家自然科学基金1项、省部级项目3项。承担《药物合成反应》研究生课程一门。

研究领域

多组分反应、不对称催化、超分子催化、药物合成。

代表性文章

[1] Xiaochu Ma, Jun Jiang, Siying Lv, Wenfeng Yao, Yang Yang, Shunying Liu*, Fei Xia and Wenhao Hu*, A YlideTransformation of Rh(I) Carbene: Enantioselective Three-component Reaction via Trapping of Rh(I) Associated Ammonium Ylides by β-Nitroacrylates, Angew. Chem. Int. Ed. 2014, Angew. Chem. Int. ed. 53(48), 13136-13139, 2014.

[2] Jiang Jun, Ma Xiaochu, Ji Changge, Guo Zhengqiu, Shi Taodao, Liu Shunying*, Hu Wenhao*. Ruthenium(II)/Chiral Brønsted Acid Co-Catalyzed Enantioselective Four-Component Reaction/Cascade Aza-Michael Addition for Efficient Construction of 1,3,4-Tetrasubstituted Tetrahydroisoquinolines, Eur. Chem.J. 20(6), 1505-1509, 2014.

[3] Lin Qiu,Xin Guo,Chaoqun Ma,Huang Qiu,Shunying Liu,*Liping Yanga andWenhao Hu*. Efficient synthesis of chiral cyclic acetals by metal and Brønsted acid co-catalyzed enantioselective four-component cascade reactions, Chem. Commun., 50, 2196-2198, 2014.

[4] Lin Qiu, Lixin Gao, Jixing Tang, Dongwei Wang, Xin Guo, Shunying Liu,*, Liping Yang, Jia Li, and Wenhao Hu*, Regio- and Diastereoselective Construction of α‑Hydroxy-δ-amino Ester Derivatives via 1,4-Conjugate Addition of β,γ-Unsaturated N‑Sulfonylimines, J. Org. Chem. 79, 4142−4147, 2014.

[5] Zhongshi Liang, Xingui Li, Yegui Xie and Shunying Liu.* ‘Smart’ gold nanoshells for combined cancer chemotherapy and hyperthermia, Biomed. Mater. 9, 025012-025022, 2014.